University of Manchester
Stem cells provide clues to cancer spread

Scientists have made a breakthrough in understanding how cancers spread in what could lead to new ways of beating the disease.

The University of Manchester study used embryonic stem (ES) cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.

Dr Chris Ward, in the University’s Faculty of Medical and Human Sciences, studied a crucial change that makes cancer cells able to start moving and spread into other tissues.

Normal cells, as well as early cancer cells, are called epithelial cells because they bind tightly to each other forming stable layers of tissue. However, as a tumour becomes more advanced, some of the cells change to become �mesenchymal’.

Mesenchymal cells do not bind to each other, forming more disorganised tissues in which the cells can move around. Since this crucial change – known as the epithelial-mesenchymal transition, was first observed in the early embryo, Dr Ward theorised that embryonic stem cells might undergo a similar process.

Dr Ward, whose findings are published in the journal Molecular Biology of the Cell, said: "We have shown that ES cells spontaneously change in a manner that is remarkably similar to the epithelial-mesenchymal transition. They lose the proteins that cells use to bind to each other and have other protein alterations that are characteristic of spreading cancer cells.

www.americanchronicle.com
By Alien Sheng
Herbal Home Remedies for Dark Circles Under Eyes

Dark under eye circles is the most common thing that can be seen in almost every individual. Around 8-9 out of 10 people have dark circles under the eyes.

Causes of Dark under eye circles

Age: With the preceding age the skin becomes thinner and the veins under the eyes become more prominent.

Fatigue or Lack of Sleep

Due to Stress or depression

Due to inbalanced diet

Hyper pigmentation

Sun exposure

Excessive use of drugs and medicines

Home Remedies

www.chillicothegazette.com
BY JANET VOINOVICH
Shield your skin for a healthy tomorrow

As summer approaches, George and I can't help but think about how much we love the outdoors. After a long, cold winter, we can't wait to get outside into the sunshine to enjoy the natural beauty of Ohio and breathe in the fresh air. This passion for healthy living also means doing everything possible to protect ourselves and our family from skin cancer - especially during the warm summer months.

Studies have shown people are more worried about getting cancer than diseases like Alzheimer's and diabetes. Surprisingly, however, they don't realize many of the deadliest skin cancers can be prevented or detected early.

Raising awareness is quite possibly the most important thing we can do to prevent skin cancer. That is why we've designated May as Melanoma/Skin Cancer Detection and Prevention Month.

Today, skin cancer is the most common and fastest growing form of cancer in the United States and it affects more than one million people each year. One person dies every hour from melanoma, the deadliest form of the disease. The American Cancer Society estimates that there will be 2,390 new cases of melanoma in Ohio this year. Sadly, many of these cancers could have been prevented.